Welcome to cr.appliance

cr.appliance is an independent, high-experienced expert team in early clinical drug development.

Since more than 10 years the team supports its clients in the healthcare industry with a broad range of counseling and hands-on services around drug development and licensing.

  • High-quality and scientific consultancy in drug development and licensing
  • Sustainable and successful drug development concepts
  • Value- and time-optimized drug development programs
  • State-of-the-art clinical study designs and concepts
  • Competent and smart medical and scientific writing
  • Many customer-specific services in various aspects
  • In-house training courses

cr.appliance participates actively in several expert and regulatory networks.

Karen Grave-Hermann, Dr. Robert Hermann
Karen Grave-Hermann, Dr. Robert Hermann


New Publications

Hermann R, Litwin JS, Friberg LE, Dangond F, Munafo A. Effects of cladribine tablets on heart rate, atrio-ventricular conduction and cardiac repolarization in patients with relapsing multiple sclerosis. Br J Clin Pharmacol. 2019;1-11. https://doi.org/10.1111/bcp.13919 Derendorf... Read More

New website and review articles

New website launched on January 15th, 2019. New review article on drug-drug and food-drug interactions available: Core Entrustable Professional Activities in Clinical Pharmacology: Pearls for Clinical Practice. Drug-Drug and Food-Drug Interactions. J Clin Pharmacol 2018;... Read More

… more news and archive